This study concludes that Mondia whitei may have an effect on male fertility, leading to a decrease in sperm count, morphology, motility, and vitality. Research has demonstrated that Mondia Whitei can improve memory, learning speed, and retention. In particular, roots or dust are known to increase alertness and energy in many people. The observed increase in testicular protein content and weight may be due to the action of testosterone.
Mondia whitei can be used as an alternative medicine to treat men with asthenozoospermia (lower than the reference value for motility) and erectile dysfunction. Mondia Whitei can be effective for both sexes, although it primarily works by increasing testosterone levels and is therefore more specific to men. As a food, mukombero contains a wide range of vitamins (A, D, K, and E), minerals (magnesium, iron, zinc, and calcium), and proteins. This increase in sperm density observed in the epididymal tail of treated rats confirms the androgenic effect of Mondia whitei.
The study suggests that mukombero has aphrodisiac properties, which is consistent with its traditional use as an aphrodisiac. Third World Medicine magazine reports that treating guinea pigs with mukombero extracts induced a significant increase in testosterone, the main male sex hormone. The long-term effect of Mondia Whitei is that it provides a powerful sexual tonic that increases libido, performance, and pressure in both sexes. This is because it acts on the central nervous system by altering the concentration of specific sex hormones (testosterone, estrogen, and progesterone).
In addition, roots or dust can help prevent diseases and disorders (STIs) that affect the functioning of the male and female reproductive systems of men or women at all stages of life. Studies have shown that chronic treatment of rats with Mondia whitei induced a significant increase in serum and testicular testosterone levels, testicular protein content, and sperm density. The inhibition of this isoenzyme increases the reserves of cGMP, the second messenger of nitric oxide and a mediator of penile vasodilation. This relaxes smooth muscle cells in the corpus cavernosum and increases blood flow to the cavernous spaces.